The methods use dinthe system and integrative biology with the aim of understanding normal and disease states (e.g., cancer, diabetes, etc.). Analysis of the genome functions as an important step to wards finding new molecules (drugs) which could target proteins in diseased cells. Gene expression, genetic chips, their applications (e.g. In the identification of genes found in different cell types or different cell states), steps in experiments with genetic chips, quantitative interpretation of the results, normalization, analysis of differential gene expression, basic statistical analysis of the results and their visualization and numerical interpretation, as well as classification and clustering of data.